Contract Research

Microsome based research

Please Contact Us to discuss

  • Bespoke blends of different Cytochrome P450 enzymes mimicking the human liver.
  • Do your compounds require further investigation on specific P450 substrates, P450 inhibitors or the formation of toxic metabolites?
  • Do you need a specific P450 from mammalian or plant species? We offer services in cloning & expression of P450s of your choice in baker's yeast or insect cells.
  • Do you need to use human hepatocytes, human liver microsomes or human liver cell lines? We offer services in compound profiling (i.e. inhibition of P450 enzymes and induction of P450 genes/proteins)
  • Or anything else you may have in mind.

Other research - Non microsome based

  • DMBioscience has brought together scientists confident in the construction and expression of hetrologous proteins in a variety of cell types (baker's yeast, insect and mammalian cells, and bacteria) and we are pleased to offer this expression service to you.
  • With our outstanding Inventory we can consider a vast range of other services for you (i.e. establishing protein kinase assays and cell cycle profiling of compounds using FACS analyses). Please Contact Us to discuss how we can assist your development.

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